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Wuhan JCJ Logis Co., Ltd.

168273-06-1 , Rimonabant, Halobetasol Propionate manufacturer / supplier in China, offering White Crystalline Powder Weight Loss Steroid Rimonabant CAS; 168273-06-1 , Polypeptide Lyophilized Powder Gonadorelin for Body Growth 2mg/10mg/Vial, Lyophilized Powder Peptides Hexarelin Muscle Gain 2mg/Vial Hex Examorelin and so on.

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Supplier Homepage Product Steroid Powder White Crystalline Powder Weight Loss Steroid Rimonabant CAS; 168273-06-1 

White Crystalline Powder Weight Loss Steroid Rimonabant CAS; 168273-06-1 

FOB Price: US $1 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1/ g
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Port: Shenzhen, China
Production Capacity: 50kg/Day
Payment Terms: L/C, T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 168273-06-1 
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Usage: Rimonabant Is a Selective Antagonist of CB1 with I
  • Appearance: White Crystalline Powder
  • Market: Global
  • Trademark: JCJ
  • Specification: USB
  • HS Code: 2969
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP
  • State: Powder
  • CAS: 168273-06-1  
  • Grade: Pharmaceutical Grade
  • Brand: Njbn Steroid
  • Color: White
  • Transport Package: Customized
  • Origin: China(Mainland)
Product Description
White Crystalline Powder Weight loss Steroid Rimonabant CAS 168273-06-1 
 
 
 Weight loss Steroid Quick Details:
 
Product NameRimonabant
CAS No168273-06-1
MFC22H21Cl3N4O
MW463.79
Mol File168273-06-1.mol
Assay99%
Storage temp2-8°C
UsageRimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane
ShippingEMS , FedEx , TNT , DHL , UPS
DeliveryExpress Courier
BrandNJBN STEROID
AppearanceWhite Crystalline Powder
Export MarketsGlobal
SampleFree
PackageDiscreet and safe packages according to different countries
Product Categories:Weight Loss;SR141716
 
Weight loss Steroid Description:
 
1.Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the  receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. It was rejected for approval for use in the United States. This decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.
2.Rimonabant, also known as SR141716, was the first selective central  (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.1 It is widely used as a tool to investigate CB receptor properties and the mechanisms by which CB agonists exert their pharmacological effects. In rodent models and clinical trials, rimonabant effectively induces lipolysis, reduces hepatomegaly, decreases body weight, and improves dyslipidemia by reducing triglyceride, free fatty acid, and total cholesterol levels and by increasing HDL/LDL ratios.2 However, rimonabant reportedly produces adverse psychiatric and neurological effects (e.g., depression or anxiety) and therefore is not approved by the FDA for use as a weight control medication. Rimonabant elicits antiproliferative and immunomodulatory effects (e.g., cell cycle arrest, increased expression of IκB and phosphorylated Akt, and decreased expression of NF-κB, phosphorylated ERK1/2, COX-2, and iNOS) in vitro.3.Rimonabant (Acomplia/Zimulti) is a new drug, the first in its class, indicated for weight loss in obese or overweight patients with co-morbidities. Different trials have also shown that it could improve HbA1c and lipid profiles (increased HDL and reduced triglyceride) in overweight or obese patients. Its use was associated with occurrence of psychiatric adverse events, although most of the patients with various kinds of depressive symptoms did eventually recover with or without anti-depressants drugs. Other common adverse events were anxiety, insomnia, mood alterations with depressive symptoms, depressive disorders, dizziness, nausea, diarrhoea, vomiting, and asthenia/fatigue.
3.Rimonabant was approved in Europe and was first marketed in the UK in 2006. In July 2007, the Committee for Medicinal Products for Human Use (CHMP) recommended some changes to the prescribing information. CHMP recommended that rimonabant not be prescribed in patients with ongoing major depression or in patients taking antidepressants. CHMP also warned that treatment with rimonabant should be stopped if a patient develops depression, including additional information on the psychiatric safety of rimonabant.In November 2008, the marketing authorisation of rimonabant was suspended in all the Member States in which the product was being marketed; and in December 2008, the marketing authorisation holder (MAH) responsible for rimonabant, Sanofi-Aventis, voluntarily withdrew its marketing authorisation. In January 2009, the European Commission withdrew the marketing authorisation for rimonabant on the ground of negative benefit-risk balance based on post-marketing data.
 
 Weight loss Steroid Application:

1.Rimonabant hydrochloride (SR-141716A) is a potent and selective CB1  inverse agonist/antagonist with a Ki of 1.6 nM, minimal affinity for CB2, and and some GPR55 agonist activity. Rimonabant was developed as an anti-obesity drug because of its appetite suppressant activity, but was taken off the market because of side effects of depression and anxiety.
2.Trials of Rimonabant over the last few years have shown it to be an effective weight loss aid for some people. It was found that, of those taking 20mg tablets of Rimonabant, a third lost over 10% of their initial body weight, while over 60% lost over 5%. Average waist measurements are reported to have reduced by between 6 and 9 cm (3-4 inches).Patients followed a low calorie diet while taking the drug, and achieved better results than a control group following a low calorie diet and taking a placebo.Participants in these trials also showed improved glucose control, cholesterol and triglyceride measurements from blood fats. These results show improvements of beyond what is expected from normal weight loss. For this reason, Rimonabant is believed to have positive effects on these measures. High-Density lipoprotein cholesterol (The good cholesterol) measures had also improved beyond expected levels.
3.Rimonabant is used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood. It can also prevent the risk of cardiovascular disease.

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Why you choose Us :
 
1.High quality with competitive price
 
1)Purity≥ 99%
2)We are manufacturer and can provide high quality products with factory price,offering free samples to test, a few shipping fee only.
 
2.Flexible Payment term
We accept every payment term as if you could imagine,such as T/T , Bitcoin , Money Gram , Western Union.
 
3.Fast and safe delivery
 
1)Parcel can be sent out in 24 hours after payment ; tracking numbers are available.
2)Secure and discreet shipment;various transportation methods for your choice.
3) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
4)We have special way could ship 0.02kg to sveral kg products a time. we offer melting powder into liquid service. and ship the liquid in special bottles.
5)Offer the latest tracking number for you to check
 
4.We have clients throughout the world
 
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
 
5.Good after-sales service 
 
1)Tell the package update ASAP, and will try our best to solve when customer encountered various problems.
2)We will teach you recipes and instructions for all kind of steroid to turn powder into liquid, and liquid become sterile ones.
 
Contacting Information :
Contact person:Kitty
 

Hi,I'm Lesley,everybody is taking the similar words,what I want to say is:Just give me a chance,Just have a try on me,maybe you will get a big surprise on me,come to join us,Buddy!
 
 
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