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Antihistaminic, Fexofenadine HCl, 153439-40-8 manufacturer / supplier in China, offering Antihistaminic Intermidiates Powder Fexofenadine HCl to Treat Seasonal Allergic Rhinitis, Factory Price Steroid Powder 17-Alpha-Methyl-Testosteron, Steroid Anabolic Dutasteride/Avodart Powder for Male Enhancement 164656-23-9 and so on.

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Supplier Homepage Product Pharmaceutical APIs Raw Material Antihistaminic Intermidiates Powder Fexofenadine HCl to Treat Seasonal Allergic Rhinitis

Antihistaminic Intermidiates Powder Fexofenadine HCl to Treat Seasonal Allergic Rhinitis

FOB Price: US $1 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1/ g
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Port: Shenzhen, China
Production Capacity: 1500kg
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 153439-40-8
  • Customized: Non-Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • Certificates: ISO9001
  • Express Way: EMS, FedEx, TNT, DHL, Hkems
  • Trademark: JCJ
  • Specification: usp
  • HS Code: 2942000000
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP, BP
  • State: Powder
  • Delivery Time: Within 3-5 Days After Payment
  • Grade: Pharmaceutical Grade
  • Export Market: Global
  • Transport Package: Customized
  • Origin: China
Product Description
Antihistaminic Intermidiates Powder Fexofenadine Hcl to Treat Seasonal Allergic Rhinitis

Basic Details:

Product Name: Fexofenadine hydrochloride 
Synonyms: FEXOFENADINE-D10 HCL;α,α-dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]benzeneacetic acid;Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride;MDL 16455A;Telfast;Telfast BD;2-[4-[1-Hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride;Allegra 
CAS: 153439-40-8 
MF: C32H40ClNO4 
MW: 538.12 
Product Categories: Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;Aromatics;Heterocycles;Metabolites & Impurities;API 
mp  148-150oC 
storage temp.  -20°C 
Chemical Properties Off-White Crystalline Solid 
Usage A metabolite of of terfenadine, a H1-Histamine receptor antagonist 
Usage The active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. 
Usage Antihistaminic;histamine H1-receptor antagonist .

COA:

 
Product name  fexofenadine hcl
CAS No. 153439-40-8Outer Packing  25KG/DRUM
Production date MARCH 2015Shelf life FEB.2020
Standard adopted  USP 38
Items of analysisSpecificationResults
  description  a white or almost white crystalline powder  almost white crystalline powder
  solubility  freely soluble in methanol and ethanol,very slightly soluble in acetone,and insoluble in hexance.  complies
  identification  
  A. By I.R.  determine by infrared absorption spectrophotometry.compare the spectrum with that obtained with fexofenadine hydrochloride RS or with the referrence spectrum of fexofenadine hydrochloride.  complies
  B. By HPLC  the retent ion time of the major peak as obtained in the assay test of the sample solution corresponds to that of the standard solution.  complies
  C.Chlorides  a white precipitate should be formed  complies
  water(by KF% W/W)  not more than 2%  0.22%
  residue on ignition(% w/w)  not more than 0.1%  0.06%
  content of chloride(on anhydrous basis % w/w)  NLT 6.45% and NMT 6.75%  6.55%
  heavy metals(ppm)  not more than 20ppm  less than 20 ppm
  related compounds(by HPLC)  
  related compound A  NMT 0.20%  0.01%
  decarboxylated degradant  NMT 0.15%  Not detected
  any other unkonwn impurity  NMT 0.10%  0.052%
  total impurities  NMT 0.5%  0.15%
  limit of fexofenadine related compound   not more than 0.20%  0.11%
  assay(By HPLC,%w/w)(on anhydrous basis)  not less than 98.0% and not more than 102.0%  99.13%
  methanol  NMT 3000  278.59
  ethanol  NMT 5000  not detected
  isopropyl chloride  NMT 15  not detected
  isopropyl alcohol  NMT 5000  311.36
      
  tetra hydro furan  NMT 720  not detected
  methylene dichloride  NMT 600  not detected
  ethyl acetate  NMT 5000  60.22
  isopropyl acetate  NMT 5000  not detected
  toluene  NMT 890  6.25
  methyl isobutyl ketone  NMT 5000  1979.5
  acetone  NMT 5000  not detected
  particle size  90% should pass through 100 microns  complies
ConclusionQualified

Description:

Fexofenadine, sold under the trade name Allegra among others is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.Therapeutically, fexofenadine is a selective peripheral H1-blocker.

Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines.It has also been called a third-generation antihistamine, although there is some controversy associated with the use of the term.

Fexofenadine has been manufactured in generic form since 2011.

Medical uses:

Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of chronic urticaria.It does not cure but rather prevents the aggravation of allergic rhinitis and chronic idiopathic urticaria and reduces the severity of the symptoms associated with those conditions, providing relief from repeated sneezing, runny nose, itchy eyes or skin, and general body fatigue.

How to use Fexofenadine HCL:

If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this medication. If you have any questions, consult your pharmacist. If your doctor has prescribed this medication, take it as directed, usually 2 times daily (every 12 hours).

If you are using the liquid form of this medication, shake the bottle well before each dose and measure the dose carefully using a special measuring device/spoon.


Antihistaminic Intermidiates Powder Fexofenadine HCl to Treat Seasonal Allergic Rhinitis

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Why you choose Us:
 
1.High quality with competitive price

1)Purity≥ 99%
2)We are manufacturer and can provide high quality products with factory price,offering free samples to test, a few shipping fee only.
 
2.Flexible Payment term
We accept every payment term as if you could imagine,such as T/T , Bitcoin , Money Gram , Western Union.
 
3.Fast and safe delivery

1)Parcel can be sent out in 24 hours after payment. Tracking numbers available
2)Secure and discreet shipment. Various transportation methods for your choice.
3) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
4)We have special way could ship 0.01kg to sveral kg products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.
5)Offer the latest tracking number for you to check
 
4.We have clients throughout the world.

1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
 
5.Good after-sales service 
1)Tell the package update ASAP, and will try best solve when customer encountered various problems.
2)we will teach you recipes and instructions for all kind of steroid to turn powder into liquid, and liquid become sterile ones.
 
How to proceed your orders:
 
Step 1:Please let me know the items you are favorable, quantities, and the destination country.
Step 2:You confirm all details, and offer us purchasing order.
Step 3:We send the detail price of our product and offer the suitable shipping method for reference.
Step 4:You confirm the order and pay money 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number,ZIP code and your special requirements.
Step 5:We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
Step 6:We offer good after-sales service after you receive parcel.

If you are interested in this kind of products, pls feel free to send me email or call me directly.
+86 18872220738

Welcome your inquiry ! ^_^
Debbie


 
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