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Analgesic, Antipyretic, Verapamil HCl manufacturer / supplier in China, offering Analgesic / Antipyretic Drug Verapamil HCl CAS: 152-11-4 Anti-Hypertension, Mupirocin Raw Powder CAS: 12650-69-0 for Skin Infections Treatment, Fermentative Weight Loss Supplement Orlistat Raw Powder CAS: 96829-58-2 and so on.

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Analgesic / Antipyretic Drug Verapamil HCl CAS: 152-11-4 Anti-Hypertension

FOB Price: US $1-5 / Gram
Min. Order: 10 Gram
Min. Order FOB Price
10 Gram US $1-5/ Gram
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Port: Shenzhen, China
Production Capacity: 100000kg
Payment Terms: T/T, Western Union, Paypal, Bitcoin

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Basic Info
  • Model NO.: 152-11-4
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Delivery Time: 5-7 Hours
  • Trademark: Steroid
  • Specification: powder
  • HS Code: 156793
  • Powder: Yes
  • Certification: ISO 9001, USP, BP
  • State: Solid
  • Shipping Time: Within 24 Hours
  • Shipping Method: DHL, FedEx, TNT, Hkems, EMS
  • Transport Package: Customized
  • Origin: China
Product Description
Analgesic / Antipyretic Drug Verapamil HCL CAS: 152-11-4 Anti-hypertension

Quick Details:

Product Name: (+/-)-Verapamil hydrochloride 
Synonyms: R(+)-VERAPAMIL HYDROCHLORIDE;(+)-VERAPAMIL, METHOXY-, HYDROCHLORIDE;5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-valeronitril;cordilox;d-365hydrochloride;finoptin;iproveratrilhydrochloride;izoptinhydrochloride 
CAS: 152-11-4 
MF: C27H39ClN2O4 
MW: 491.06 
EINECS: 205-800-5 
Product Categories: Miscellaneous Biochemicals;Organics;Calcium channel;Ion Channels;TYLENOL;antibiotic;Cardiovascular APIs mp  142 °C (dec.)(lit.)
storage temp.  Refrigerator (+4°C) 
solubility  H2O: >30 mg/mL
form  solid
color  white
Water Solubility  soluble 
Merck  13,10012 
Chemical Properties : White to off-white powder 
Usage : analgesic, antipyretic 
Usage : Bromhexine metabolite, sodium channel blocker, decongestent secretolytic agent for respiratory diseases.

COA:

 
Product name  Verapamil HCL
CAS No. 152-11-4Outer Packing 10kg/drum 
Production date 2016/12/23Shelf life 2 years
Standard adopted USP35 
Items of analysisSpecificationResults
 Infrared ectrophotometry:  should be positive  Complies 
  HPLC:  should be positive  Complies 
 Generally identify:  Show chloride reaction  Complies 
  (Description) A white crystalline powder  Complies 
  (Melting Range) 140.0~144.0ºC   140~142ºC 
 PH  4.5~6.5  4.9 
  (Loss on drying)  ≤0.5%  Not more than 0.5% 0.06% 
    (Residue on Ignition)  Not more than 0.1%  n. m. t. 0.1% 0.06% 
  (Related substances) Total impurity ≤0.5%,  impurity is not more than 0.5% 0.08% 
  (Related substances) Single impurity≤0.30%  Not more than 0.30% of single impurity & the sum of all 0.04% 
  (Organic residual solvent) Acetone<5000ppm,  Complies 
  (Organic residual solvent) Toluene<890ppm  Complies 
  (Organic residual solvent) Chloroform<60 ppm  Complies 
  (Assay)  C27H38N2O4·HCL  Calculate on dried basis C27H38N2O4·HCL 99.0-101.0%  99.5% 
ConclusionQualified

Description:

Verapamil Hydrochloride is the hydrochloride form of Verapamil, which is a phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)

Medical uses:

Verapamil is used for controlling ventricular rate in supraventricular tachycardia and migraine headache prevention.It is a class-IV antiarrhythmic and more effective than digoxin in controlling ventricular rate.[11] Verapamil is not listed as a first line agent by the guidelines provided by JAMA in JNC-8.However, it may be used to treat hypertension if patient has co-morbid atrial fibrillation or other types of arrhythmia.

Verapamil is also used intra-arterially to treat cerebral vasospasm. Verapamil is used to treat the condition cluster headache.

Mechanism of Action:

Essential Hypertension

Verapamil exerts antihypertensive effects by decreasing systemic vascular resistance, usually without orthostatic decreases in blood pressure or reflex tachycardia; bradycardia (rate less than 50 beats/min) is uncommon (1.4%). During isometric or dynamic exercise verapamil does not alter systolic cardiac function in patients with normal ventricular function.

Verapamil does not alter total serum calcium levels. However, one report suggested that calcium levels above the normal range may alter the therapeutic effect of verapamil.

Analgesic / Antipyretic Drug Verapamil HCl CAS: 152-11-4 Anti-Hypertension

Packaging:


We have professional team for package and shipment.Special way to ship 100 ml to 100L liquids at one time to your country.Fast and discreet shipment could be arranged for customs pass Guaranteed.

Competitive Advantage:

 
1.We have engaged in this line has many years of experience, our reputation is our guarantee of quality.High quality, competitive price, fast delivery, safe shipping and considerate after-sale service gain the trust and praise from the customers all over the world.
2.Saichuang Technology Co., ltd is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
3.Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
4.Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed.100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil;98% pass to Germany, Russia, Australia, New Zealand.
5.Our products and services will focus on the largest customer demand,We hold the greatest enthusiasm and sincere cooperation with each customer.

We supply a variety of chemicals with competitive price and high quality including:
Food additive
Feed additive
Pharmaceutical raw materials
Steroid hormone
Cinnamate series
Pesticides
Veterinary medicine
Flavoring and essence
Plant extract
Paint and coating
Inorganic chemicals
Organic chemicals
Amino acid,
Vitamins.

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3.You confirm the order and pay money 100% in advance and send us the detailed address.
4.We will pack your parcel and arrange to shipment according to your requirements
5.Once parcel is sent,I will offer you parcel's picture,tracking number and tracking website.
6.After you receiving parcel,we will offer you best after-sale.

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