Antiprotozoal Drug Ritodrine Hydrochloride CAS: 23239-51-2 to Stop Premature Labor
|FOB Price:||US $1 / g|
|Min. Order:||10 g|
|Min. Order||FOB Price|
|10 g||US $1/ g|
|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: 318-98-9
- Customized: Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Certificates: ISO9001
- Express Way: EMS, FedEx, TNT, DHL, Hkems
- Trademark: JCJ
- Specification: usp
- HS Code: 1502009000
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Powder
- Delivery Time: Within 3-5 Days After Payment
- Grade: Pharmaceutical Grade
- Export Market: Global
- Transport Package: Customized
- Origin: China
Product Name: Ritodrine hydrochloride
Synonyms: du21220;erythro-p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzylalcoholhy;p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)-benzylalcohohydrochl;pre-par;utopar;RITODRINE HCL;RITODRINE HYDROCHLORIDE;N-[P-HYDROXYPHENETHYL]-4-HYDROXY-NOREPHEDRINE HYDROCHLORIDE
Product Categories: Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;RIDZOL;API
storage temp. -20°C Freezer
Chemical Properties Off-White Solid
Usage A β2-Adrenergic agonist.
|Product name||Ritodrine Hydrochloride|
|CAS No.||23239-51-2||Outer Packing||1kg/bag|
|Production date||Sep.04,2015||Shelf life||Sep.03,2017|
|Items of analysis||Specification||Results|
|Appearance||A white or almost white,crystalline powder||conforms|
|Identification||The IR absorption apectrum of a potassium bromide dispersion of it exhibits maxima only at the same wavelengths as that of a similar preparation of USP Ritodurine Hydrochloride RS||conforms|
|Identification||The retention time of the ritodrine hydrochloride in the Assay preparation obtained in the Assay corresponds to that of the standard preparation obtained in the assay||conforms|
|Identification||A solution (1 in 100) responds to the tests for chloride.||conforms|
|PH||between 4.5 to 6.0||5.4|
|Loss on Drying||≤0.1%||0.19%|
|Residue on ignition||≤0.2%||0.02%|
|Any individual impurity||≤0.5%||0.04%|
|Assay||between 97.0% to 103.0%||98.8%|
Ritodrine (trade name Yutopar) is a tocolytic drug used to stop premature labor.This drug has been removed from the US market, according to FDA Orange Book. It was available in oral tablets or as an injection and was typically used as the hydrochloride salt, ritodrine hydrochloride.
Ritodrine is a short-acting β2 adrenoreceptor agonist - a class of medication used for smooth muscle relaxation (other similar drugs are used in asthma or other pulmonary diseases such as salbutamol (albuterol)). Since ritodrine has a bulky N-substituent, it has high β2 selectivity. Also, the 4-hydroxy group on the benzene ring is important for activity as it is needed to form hydrogen bonds. However, the 4-hydroxy group makes it susceptible to metabolism by catechol-O-methyl transferase (COMT). Since it is β2-selective it is used for premature labor.
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