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Wuhan JCJ Logis Co., Ltd.

Yohimbine HCl, Dapoxetine Hydrochloride, Hydrocortisone Acetate manufacturer / supplier in China, offering Dapoxetine Hydrochloride Steroid Powder Sex Enhance Hormones with Safe Shipping, Factory Sell High Quality Dienogestrel Female Hormones, High Purity Quality Estradiol Valerate Female Hormones and so on.

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Supplier Homepage Product Steroid Powder Dapoxetine Hydrochloride Steroid Powder Sex Enhance Hormones with Safe Shipping

Dapoxetine Hydrochloride Steroid Powder Sex Enhance Hormones with Safe Shipping

FOB Price: US $1 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1/ g
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Port: Shenzhen, China
Production Capacity: 1500kg
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: CAS: 119356-77-3
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Delivery Time: Within 3-5 Days After Payment
  • Grade: Pharmaceutical Grade
  • Export Market: Global
  • Transport Package: Customized
  • Origin: China
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP
  • State: Powder
  • Name: Dapoxetine Hydrochloride
  • Certificates: ISO9001
  • Express Way: EMS, FedEx, TNT, DHL, Hkems
  • Trademark: JCJ
  • Specification: usp
  • HS Code: 456789
Product Description
Basic Info.
Model NO.:cas 119356-77-3
 
Powder:Yes
Customized:Non-Customized
 
Certification:ISO 9001, USP
Suitable for:Adult
 
State:Solid
Purity:>99%
 
CAS:119356-77-3
Appearance:White to off-White Cyrstalline Solid
 
Trademark:JCJ
Package:Best Safe Methods
 
Specification:medical grade
Origin:China
Product Description
Steroids Powder Dapoxetine Muscle Gaining Anabolic Steroids Hormones

Quick Detail:
Alias: Dapoxetine
CAS: 119356-77-3
Usage: Bodybuilding , Muscle Gaining
Assay: 98% min.
MF: C21H23NO.ClH
MW: 341.88
Character: White to Off-White Cyrstalline Solid, odorless, slight sweet taste.
Half life : 18.7 hours (30 mg dose) and 21.9 hours (60 mg dose).

Description
Dapoxetine is a white powder substance and water-soluble. Taken 1-3 hours before sexual activity, it is rapidly absorbed in the body. Its maximum plasma concentration (Cm) is reached 1-2 hours after oral administration.
Dapoxetine can be taken with or without food.

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that was designed specifically for premature ejaculation.  SSRIs have been shown to be effective for the treatment of PE.  The downside to most SSRIs is that they must be taken daily in order to achieve the desired effect. Dapoxetine was designed to be taken on an "as needed" basis and has been shown to be effective when taken < 3 hours before sexual activity.  Studies have shown that dapoxetine increases the intra-vaginal ejaculation latency time (IELT) - the time from vaginal penetration to male orgasm.
 
Dapoxetine, (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) for men at th age of 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, so as to delay ejaculation.. As a member of selective serotonin reuptake inhibitor (SSRI) family, Dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, Dapoxetine is absorbed and eliminated rapidly in the body. Its fast response makes it suitable for the treatment of PE but not as an antidepressant.

Applications:
In Dresser study (2006), plasma concentration of 24 subjects was obtained. Half of the sample pool were treated with dapoxetine 60 mg + tadalafil 20 mg; the other half were treated with dapoxetine 60 mg + 100 mg. These plasma samples were then analyzed using liquid chromatography-tandem mass spectrometry. The results showed that dapoxetine does not alter the pharmacokinetic of tadalafil .

Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction.
Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

The News On Treat Premature Ejaculation:
To treat premature ejaculation, both psychological and physiological factors need to be managed. From a pharmacological point-of-view, to treat the physiological aspect of premature ejaculation, dapoxetine hydrochloride is one of the first oral drugs to be made available. Psychological treatment may be given concomitantly, as the condition is multifactorial.
 
One of the possible adverse effects reported with SSRIs when used to treat depression is delayed ejaculation. This reported adverse effect led to the studies of dapoxetine hydrochloride, using the effect therapeutically. It is thought that serotonin may be involved in the inhibition of ejaculation. By blocking the serotonin reuptake in men suffering from premature ejaculation, the time to ejaculation may be prolonged.
 

 

30 mg as needed

60 mg as needed

Placebo

Nausea

11.0

22.2

2.2

Dizziness

5.8

10.9

2.2

Headache

5.6

8.8

4.8

Diarrhea

3.5

6.9

1.7

Somnolence

3.1

4.7

0.5

Fatigue

2.0

4.1

1.2

Insomnia

2.1

3.9

1.5

Nasopharyngitis

3.2

2.9

2.3

 Dosage For Use:
Initial dose: 50 mg orally once a day, as needed, 1 hour prior to sexual activity
Maintenance: 25 to 100 mg orally once a day, as needed, 1 hour prior to sexual activity
Comments: This drug may be taken anywhere from 30 minutes to 4 hours before sexual activity.

Specifications:
ITEMSSTANDARDRESULTS
CharacteristicsWhite or almost white crystalline powderWhite crystalline powder
Melting point175.0~177.0ºC174.0~179.0ºC
Specific rotatlon+128°±3(C=1,CH3OH)+128°±3(C=1,CH3OH)
Loss on drying≤0.5%0.32%
Heavy metals0ppm0ppm
Relative substance≤0.1%
Total impurity
0.07%
Assay(on drled basis)≥99.5%99.61%
ConclusionIt complies to prescrlbed enterprise standard

 
The Related Sex Enhancers:
Tadalafil is used to treat erectile dysfunction in men. Tadalafil is much longer lasting than . Effects can be felt anywhere between 36-48 hours.Tadalafil works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function
 
Vardenafil is closely related in fuction to citrate and tadalafil, structly, the difference between the vardenafil molecule and citrate is a nitrogen atom's position and the change of .
 
Dimethylthiosildenafil is derived from Citrate.Citrate is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements.
 
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Tracking numberOffered once it is released
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