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Wuhan JCJ Logis Co., Ltd.

Melanotan-1, Mt1, Mgf manufacturer / supplier in China, offering Mt-1, Melanotan-1, 10mg/Vial 75921-69-6 99% Purity Mt1, Purity 99% Methyltestosteron 17-Methyltestosterone CAS: 58-18-4 for Muscle Gain, Orlistat Raw Powder Effective Weight Loss Supplement CAS: 96829-58-2 and so on.

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Supplier Homepage Product Peptides Hgh 176-191 Mt-1, Melanotan-1, 10mg/Vial 75921-69-6 99% Purity Mt1

Mt-1, Melanotan-1, 10mg/Vial 75921-69-6 99% Purity Mt1

FOB Price: US $1 / Vial
Min. Order: 10 Vial
Min. Order FOB Price
10 Vial US $1/ Vial
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Port: Hong Kong, Hong Kong
Production Capacity: 1000kg/Month
Payment Terms: T/T, Western Union, Money Gram, BTC

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Basic Info
  • Model NO.: 75921-69-6
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Shipping Time: 1 Day for Ready Goods
  • Customs Success Rate: >99%
  • Supply Ability: Mess in Stock
  • Payment: T/T, Western Union, Money Gram, Paypal, Bitcoin
  • Guarantee: Support Resending Police
  • Transport Package: Customized
  • Origin: China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001, USP, BP
  • State: Solid
  • Appearance: White Crystalline Solid
  • Delivery: 3-5 Business Days
  • Shipping Method: DHL, FedEx, TNT, Hkems, EMS Express
  • Package: Customized Package
  • MOQ: 10vial
  • Trademark: D-Glucosamine hydrochloride
  • Specification: ISO9001
  • HS Code: 846321864
Product Description

MT-1, Melanotan-1, 10mg/vial CAS: 75921-69-6 high purity 99% in stock

The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).

Molecular formula: C78H111N21O19
Molar Mass: 1646.845
CAS: 75921-69-6
PubChem: CID 16154396
Synonyms: Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH

TEST ITEMS SPECIFICATION RESULT
1 Appearence White powder Conforms
2 Peptide Content ≥80.0% 81.0%
3 Water (KF) ≤8.0% 5.8%
4 Acetic Acid 9%~15.0% 10.5%
5 Purity(HPLC) ≥98.0% 98.3
 
Sequence:Ac-NLE-c[ASP-His-d-PHE-ARG-TRP-LYS]-NH2 Chemical Bridge Asp2-Lys7
Cas No.:121062-08-6
Molecular Formula:C50H69N15O9
Molecular Weight:1024.18
Purity (HPLC):0.98
Appearance:White powder
Single Impurity (HPLC):0.5%max
Amino Acid Composition:±10% of theoretical
Peptide Content (N%):>80.0%
Water Content(Karl Fischer):<8.0%
Acetate Content(HPIC):<10.0%
Specific Rotation (20/D):-55.0~-65.0°(c=1 1%HAc)
MS(ESI):Consistent
Mass Balance:95.0~105.0%
Package:10g/vial, 10vial/kit

COA:
AppearanceWhite to off white powderConsistent
Purity(HPLC)≥98%99.10%
Water<6.0%4.40%
Acetic Acid3.0-8.0%6.85%
Trifluoroacetic Acid<0.25%0.18%
Peptide≥80%84.56%
MSConsistentConsistent

Melanotan-1 Mechanism of Action - How it Works!
Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

Usage:

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects.

Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

MT-1(Melanotan I) Dosage

Start with a dose of 1mg daily for the first two or three days and, if level of side effects permit, look to increase dosage by 0.25mg every day over the next several days until you reach a daily dosage of 2-3mg. This level should be adequate for most users, though some may wish to increase yet further, perhaps as high as 5mg daily in order to achieve a very deep tan. A maintenance phase as described above is then used.

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Packing
Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email

Quality
Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.

Delivery
We can pack your powders within 24 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.

Price
Best prices you're sure to be satisfied, the more you buy, the more competitive prices you get.

Payment
T/T in advance , Bitcoin, Money Gram, Western Union.

Service
24/7 online after-sales service.

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