Sodium Picosulfate CAS: 10040-45-6 Laxative Medicine White Powder
|FOB Price:||US $1 / g|
|Min. Order:||10 g|
|Min. Order||FOB Price|
|10 g||US $1/ g|
|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: 10040-45-6
- Customized: Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- Certificates: ISO9001
- Express Way: EMS, FedEx, TNT, DHL, Hkems
- Trademark: JCJ
- Specification: usp
- HS Code: 1502009000
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Powder
- Delivery Time: Within 3-5 Days After Payment
- Grade: Pharmaceutical Grade
- Export Market: Global
- Transport Package: Customized
- Origin: China
Chemical Names: Sodium picosulfate; Picosulfate sodium; 10040-45-6; Laxoberon; Guttalax; Laxoberal More...
Molecular Formula: C18H13NNa2O8S2
Molecular Weight: 481.401 g/mol
InChI Key: GOZDTZWAMGHLDY-UHFFFAOYSA-L
Appearance: white powder
Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12-24 hours to work, since it works in the colon.
Abdominal cramps and diarrhea are normal effects of picosulfate and should be expected.
The use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia.Patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.
Mechanism of action:
Sodium picosulfate is a prodrug. It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridiyl)methane (DPM, BPHM).This compound is a stimulant laxative and increases peristalsis in the gut.
Sodium picosulfate is typically prescribed in a combined formulation with magnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies.
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